Кои са лекарствата, които повлияват нивото на кръвната захар?

Кои са лекарствата, които повлияват нивото на кръвната захар?

Кои са лекарствата, които повлияват нивото на кръвната захар?

Познаването на лекарствата, които могат да повлияват нивото на кръвната захар е от особено голямо значение при хората със захарен диабет. Някои лекарства намаляват нивото на кръвната захар, други го увеличават, а трети могат да оказват влияние и в двете посоки. Същевременно, трябва да се има предвид, че не всички лекарства имат едно и също влияние при различните хора.

 

 

1.   Лекарства, които могат да повишат кръвната захар и да предизвикат хипергликемия

Генерично име (Търговско име)

Abacavir (Ziagen®)

Abacavir + lamivudine,zidovudine (Trizivir®)

Acetazolamide (Diamox®)

Acitretin (Soriatane®)

Albuterol (Ventolin®, Proventil®)

Albuterol + ipratropium (Combivent®)

Ammonium chloride

Amphotericin B (Amphocin®, Fungizone®)

Amprenavir (Agenerase)

Anidulafungin (Eraxis®)

Aripiprazole (Abilify®)

Arsenic trioxide (Trisenox®)

Asparaginase (Elspar®)

Atazanavir (Reyataz®)

Atenolol + chlorthalidone (Tenoretic®)

Atorvastatin (Lipitor®)

Atovaquone (Mepron®)

Baclofen (Lioresal®)

Benazepril + hydrochlorothiazide (Lotension®)

Betamethasone  (Alphatrex®, Betatrex®, Beta-Val®, Diprolene®, Diprolene® AF, Diprolene® Lotion, Luxiq®, Maxivate®)

Betamethasone +clotrimazole (Lotrisone® )

Bexarotene (Targretin®)

Bicalutamide (Casodex®)

Bisoprolol + hydrochlorothiazide (Ziac®)

Bumetanide (Bumex®)

Caffeine

Candesartan + hydrochlorothiazide (Atacand HCT®)

Captopril + hydrochlorothiazide (Capozide®)

Carteolol (Cartrol® , Occupress® - очни капки)

Carvedilol (Coreg®)

Chlorothiazide (Diuril®)

Chlorthalidone (Chlorthalidone ®, Clorpres®, Tenoretic®, Thalitone®)

Choline salicylate

Choline salicylate + magnesium salicylate (CMT®, Tricosal®,Trilisate®)

Clobetasol (Clobevate®, Cormax®, Cormax® Scalp Application, Embeline® E, Olux®, Temovate®, Temovate® E, Temovate® Scalp Application)

Clozapine (Clozaril®, FazaClo®)

Conjugated estrogens (Estrace®, Estring®, Femring®, Premarin®, Vagifem®, Cenestin®, Enjuvia®, Estrace®, Femtrace®, Gynodiol®, Menest®, Ogen®)

Conjugated estrogens + medroxyprogesterone (Premphase®, Prempro®)

Corticosteroids

Corticotropin

Cortisone

Cyclosporine (Sandimmune®, Neoral®, Gengraf®)

Daclizumab (Zenapax®)

Decitabine (Dacogen®)

Desonide (DesOwen®, Tridesilon®)

Desoximetasone (Topicort®)

Dexamethasone (Adrenocot®, Dalalone®, Decadron®, Decaject®, Dekasol®, Dexacort®, Dexasone®, Dexim®, Dexone®, Hexadrol®, Medidex®, Primethasone®, Solurex®, Dexamethasone Intensol®)

Dextromethorphan + promethazine (Phenergan®  с Dextromethorphan, Phen-TussDM®)

Diazoxide (Proglycem®)

Enalapril + hydrochlorothiazide (Vaseretic®)

Encainide (Enkaid®)

Epinephrine (EpiPen®, EpiPen® Jr, Primatene® Mist otc)

Esterified estrogens, estrone, estropipate

Esterified estrogens + methyltestosterone (Estratest®)

Estradiol, ethinyl estradiol (Climara®, Congest®, Delestrogen®, Depo-Estradiol®, Depogen®, Estinyl®, Estrace®, Estraderm®, Estragyn 5®, Estragyn LA 5®, Estrasorb®, EstroGel®, Estro-L.A.®, Gynodiol®, Kestrone-5®, Neo-Estrone®, Menest®, Menostar®, Ogen .625®, Ogen®, Ortho-Est®, Premarin®, Valergen®, Vivelle®, Vivelle-Dot®)

Estradiol + norethindrone (Activella®)

Estradiol + norgestimate (Prefest®)

Estramustine (Emcyt®)

Ethacrynic acid (Edecrin®, Sodium Edecrin®)

Everolimus (Afinitor®)

Everolimus (Zortress®)

Fluoxetine (Prozac®, Sarafem®)

Flurandrenolide (Cordran®)

Formoterol (Foradil® Aerolizer® Inhaler)

Fosamprenavir (Lexiva®)

Fosinopril + hydrochlorothiazide (Monopril HCT®)

Furosemide (Lasix®)

Gemtuzumab ozogamicin (Mylotarg®)

Glucosamine (възможно е засилване на инсулиновата резистентност, по-изразено при интравенозно приложение)

Hydrochlorothiazide (Aldactazide®, Aldoril®, Capozide®, Dyazide®, HydroDIURIL®, Inderide®, Lopressor® HCT, Maxzide®, Microzide®, Moduretic®, Timolide®, Vaseretic®)

Hydrochlorothiazide + irbesartan (Avalide®)

Hydrochlorothiazide + lisinopril (Prinzide®, Zestoretic®)

Hydrochlorothiazide + losartan (Hyzaar®)

Hydrochlorothiazide + metoprolol (Lopressor HCT®)

Hydrochlorothiazide + moexipril (Uniretic®)

Hydrochlorothiazide + quinapril (Accuretic®, Quinaretic®)

Hydrochlorothiazide + telmisartan (Micardis HCT®)

Hydrochlorothiazide + valsartan (Diovan HCT®)

Hydrocortisone

Indapamide (Lozol®)

Indinavir (Crixivan®)

Interferon alfa-2a (Roferon-A®)

Interferon alfa-2b (Intron-A®)

Interferon alfa-2b + ribavirin (Rebetron®)

Interferon alfa-n1 (Alferon-N®)

Irinotecan (Camptosar®)

Isoniazid (Laniazid®, Nydrazid®)

Isotretinoin (Accutane®)

Lamivudine (Epivir®, Epivir-HBV®)

Levalbuterol (Xoponex®, Xopenex HFA®)

Levonorgestrel (Plan B®, Norplant System®)

Levothyroxine (Synthroid®, Levoxyl®)

Lopinavir + ritonavir (Kaletra®)

Magnesium salicylate (Bayer Select® Backache Pain Formula, Doans® Pills, Mobidin®, Nuprin® Backache Caplet)

Medroxyprogesterone (Provera®, Depo-Provera®)

Megestrol (Megace®)

Methylprednisolone (Urbason®, Depo-Medrol®, Medrol®, Medrol®, Solu-Medrol®)

Metolazone (Zaroxolyn®, Mykrox®)

Metoprolol (Lopressor®, Lopressor® HCT, Toprol XL®)

Modafinil (Provigil®)

Moxifloxacin (Avelox®, Avelox® I.V.)

Mycophenolate (CellCept®)

Nadolol (Corgard®)

Nelfinavir (Viracept®)

Niacin, niacinamide (Niacor®, Niaspan®, Nicolar®, Nicotinex®, Slo-Niacin®)

Nilotinib (Tasigna®)

Nilutamide (Nilandron®)

Nitric oxide (INOmax®)

Norethindrone (Aygestin®, Nor-QD®, Micronor®)

Norgestrel (Orvette®)

Nystatin (Fungostatin®, Mycostatin®, Nystat-Rx®, Nystop®, Pedi-Dri®)

Nystatin + triamcinolone (Dermacomb®, Myco II®, Mycobiotic II®, Mycogen II®, Mycolog II®, Myco-Triacet II®, Mykacet®, Mykacet II®, Mytrex®, Tristatin II®)

Octreotide (Sandostatin®, Sandostatin LAR®)

Olanzapine (Zyprexa®)

Pantoprazole (Protonix®, Protonix® I.V.)

Pegaspargase (Oncaspar®)

Peginterferon alfa-2b (PEG-Intron®)

Pentamidine (Pentam 300®)

Phenylephrine* (Sudafed PE®, and others)

Phenytoin (Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Phenytek®)

Prednisolone* (AK-Pred®, Blephamide®, Blephamide® Liquifilm®, Econopred® Plus, Inflamase® Forte, Inflamase® Mild, Poly-Pred® Liquifilm®, Pred Forte®, Pred Mild®, Pred-G®, Delta Cortef®, Pediapred®, Prelone®)

Prednisone (Prednisone Intensol®, Sterapred®, Sterapred® DS)

Progesterone (Prometrium®)

Pseudoephedrine* (Claritin D®, Sudafed®, and others)
Quetiapine (Seroquel®)

Risperidone (Risperdal®, Risperdal® M-TAB®)

Ritodrine (Yutopar®)

Ritonavir (Norvir®)

Rituximab (Rituxan®)

Salmeterol (Serevent®, Serevent® Diskus®)

Salsalate (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®, Salsitab®)

Saquinavir (Invirase®)

Sodium oxybate (Xyrem®)

Somatropin (Genotropin®, Genotropin Miniquick®, Humatrope®, Norditropin cartridges®, Norditropin NordiFlex®, Nutropin®, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sotalol (Betapace®, Betapace AF®, Sorine®)

Streptozocin (Zanosar®)

Tacrolimus (Prograf®, Protopic®)

Temsirolimus (Torisel®)

Tipranavir (Aptivus®)

Tolvaptan (Samsca®)

Torsemide (Demadex®, Demadex Oral®)

Triamcinolone (Aristocort®, Aristospan®, Asthmacort®, Flutex®, Kenalog®, Tac®, Triacet®)

Ursodeoxycholic acid, ursodiol (Actigall®, Urso®)

Valproic acid, divalproex sodium (Depacon®, Depakene®, Depakene® Syrup, Depakote®, Depakote® ER, Depakote® Sprinkle)

Vitamin C (Ascorbic acid, Ascorbate)

Vitamin E (Tocopherol, Tocotrienol)

Ziprasidone (Geodone®)

 

 2.   Лекарства, които могат да намалят нивото на кръвната захар и да предизвикат хипогликемия

 

Генерично име  (Търговско име)

 

Acebutolol (Sectral®)

Acetohexamide (Dymelor®)

Alcohol

Aloe –хранителна добавка и особено ако е в комбинация с други вещества кaто: glyburide, glipizide, nateglinide, repaglinide, glimepiride, или insulin.

Amphotericin B (Ambisome®, Amphocin®, Fungizone Intravenous® Amphotec®, Abelcet®)

Amphotericin B (Abelcet®, AmBisome®)

Asian Ginseng (Ginseng; Panax ginseng)

Aspirin

Aspirin + dipyridamole (Aggrenox®)

Atenolol (Tenormin®, Tenoretic®)

Betaxolol (Betoptic®, Betoptic S® - очни капки, Kerlone® )

Bisoprolol (Zebeta®)

Bisoprolol + hydrochlorothiazide (Ziac®)

Bromocriptine (Cycloset®)

Chloramphenicol (Chloromycetin®)

Chlorpropamide (Diabinese®)

Choline salicylate (Acuprin 81®, Amigesic®, Anacin Caplets®, Anacin Maximum Strength®, Anacin Tablets®, Anaflex 750® Arthritis Pain, Ascriptin® Arthritis Pain)

Choline salicylate + magnesium salicylate C (MT®, Tricosal®, Trilisate®)

Chromium

Clarithromycin B (Klacid®, Klacar®, Klerimed®, Biaxin® )

Diazoxide (Proglycem®)

Dicumarol (Coumadin®, Miradon®)

Diltiazem (Cardizem®, Tiazac®)

Disopyramide (Norpace®, Norpace® CR)

Dorzolamide + timolol (Cosopt®)

Exenatide (Byetta®)

Fluoxetine (Prozac®, Sarafem®)

Fosphenytoin (Cerebyx®, Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Mesantoin®, Peganone®, Phenytek®)

Glimepiride (Amaryl®)

Glimepiride and Rosiglitazone (Avandaryl®)

Glipizide (Glucotrol®, Glucotrol XL®)

Glipizide and Metformin (Metaglip®)

Glyburide (Diabeta®, Glynase®, Micronase®, Glycron®)

Glyburide + metformin (Glucovance®)

Конски кестен (Aesculus hippocastanum)

Hydrochlorothiazide + metoprolol (Lopressor HCT®)

Insulin (Lantus®, Levemir®, NPH®, Humulin®, Novolin®, Apidra®, Novolog®, Humalog®)

Interferon beta-1b (Betaseron®)

Levofloxacin (Tavanic®, Levoxa® )

Liraglutide (Victoza®)

Magnesium salicylate (Bayer Select® , Doans® , Mobidin®, Nuprin®)

Metformin (Normaglic®, Glucophage®, Glucophage XR®, Metfodiab®, Metfogamma®)

Metoprolol (Lopressor®, Lopressor® HCT, Toprol XL®)

Morphine (Kadian®, MS Contin®, MSIR®, Roxanol®)

Nadolol (Corgard®)

Nateglinide (Starlix®)

Nifedipine (Adalat CC®, Procardia®, Afeditab® CR)

Octreotide (Sandostatin®, Sandostatin LAR® Depot)

Paloperidone (Invega®)

Penicillamine (Cuprimine®, Depen®)

Pentamidine (Nebupent®, Pentam 300®)

Phenelzine (Nardil®)

Phenytoin (Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Phenytek®)

Pindolol (Visken®)

Pioglitazone (Actos®)

Pioglitazone and Glimepiride (Duetact®)
Pioglitazone and Metformin (Actoplus Met®, ActoPlus Met XR®)

Pramlintide (Symlin®)

Probenecid (Benemid®, Probalan®)

Quinine (Quinamm®, Quindan®, Quiphile®, Q-vel®, Strema®)

Quinupristin + dalfopristin (Synercid®)

Repaglinide (Prandin®)

Repaglinide and Metformin (PrandiMet®)

Ritodrine (Yutopar®)

Rituximab (Rituxan®)

Rosiglitazone (Avandia®)

Rosiglitazone and Metformin (Avandamet®)

Rotigotine (Neupro®)

Salicylates

Salsalate (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®, Salsitab®)

Saxagliptin (Onglyza®)

Selegiline (Eldepryl®)

Sitagliptin (Januvia®)

Sitagliptin and Metformin HCL (Janumet®)

Sodium ferric gluconate complex (Ferrlecit®)

Somatropin (Genotropin®, Genotropin Miniquick®, Humatrope®, Norditropin cartridges®, Norditropin NordiFlex®, Nutropin, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sotalol (Betapace®, Betapace AF®, Sorine®)

Streptozocin (Zanosar®)

Sulfadiazine (Microsulfon®)

Tacrolimus P (Prograf®, Protopic®)

Tetracaine (Altacaine®, Tetcaine®, Pontocaine®)

Theophylline (Theo-24®, Theo-Dur®, TheoCap®)

Timolol (Timoptic®, Timoptic-XE®)

Tolazamide (Tolinase®)

Tolbutamide (Orinase®)

Tranylcypromine (Parnate®)

Varenicline (Chantix®)

Verapamil (Isoptin®, Calan®, Calan SR®, Isoptin SR®, Verelan®)

 

3.   Лекарства, които могат да причинят хипо- и хипергликемия


Генерично име  (Търговско име)


Amphotericin B (Ambisome®, Amphocin®, Fungizone Intravenous®, Amphotec®, Abelcet®)

Amphotericin B lipid formulations (Abelcet®, AmBisome®, Betaxolol Betoptic® {капки за очи}, KERLONE® )

Bisoprolol + hydrochlorothiazide (Ziac®)

Choline salicylate

Choline salicylate + magnesium salicylate (CMT®, Tricosal®, Trilisate®)

Darunavir (Prezista®)

Diazoxide (Proglycem®)

Fluoxetine (Prozac®, Sarafem®)

Hydrochlorothiazide + metoprolol (Lopressor HCT®)

Lanreotide acetate (Somatuline®)

Lithium (Eskalith®, Eskalith CR®, Lithobid®)

Magnesium salicylate (Bayer Select® , Doans® , Mobidin®, Nuprin®)

Mecasermin (Increlex®)

Mecasermin Rinfabate (Iplex®)

Metoprolol (Lopressor®, Lopressor® HCT, Toprol XL®)

Nadolol (Corgard®)

Octreotide (Sandostatin®, Sandostatin LAR® Depot)

Pazopanib (Votrient®)

Pentamidine (Nebupent®, Pentam 300®)

Phenytoin (Dilantin®, Phenytek®)

Rifampin (Rifadin®, Rimactane®)

Ritodrine (Yutopar®)

Rituximab (Rituxan®)

Salsalate (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®, Salsitab®)

Sunitinib (Sutent®)

Somatropin (Genotropin®, Genotropin Miniquick®, Humatrope®, Norditropin cartridges®, Norditropin NordiFlex®, Nutropin®, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sotalol (Betapace®, Betapace AF®, Sorine®)

Streptozocin (Zanosar®)

Tacrolimus P (Prograf®, Protopic®)

 

4.   Лекарства, които могат да „замаскират” хипогликемия

Генерично име  (Търговско име)

Atenolol (Tenormin®, Tenoretic® - съдържа Atenolol & Chlorthalidone)

Carteolol (Cartrol® , Occupress® - капки за очи)

Carvedilol (Coreg®)

Clonidine (Duraclon®, Catapres®)

Metoprolol (Lopressor®, Lopressor® HCT, Toprol XL®)

Nadolol (Corgard®)

Nebivolol (Bystolic®)

Pindolol (Visken®)

Propranolol (Inderal®, Inderal LA®, Inderide®, Innopran® XL, Propranolol Hydrochloride Intensol®)

Timolol (Timoptic®, Timoptic-XE®)